- Title
- Accelerating the Development of Measles and Rubella Microarray Patches to Eliminate Measles and Rubella: Recent Progress, Remaining Challenges
- Creator
- Hasso-Agopsowicz, Mateusz; Crowcroft, Natasha; Mvundura, Mercy; Mistilis, Jessica J.; Durrheim, David N.; Giersing, Birgitte; Biellik, Robin; Gregory, Christopher J.; Menozzi-Arnaud, Marion; Amorij, Jean-Pierre; Gilbert, Phillipe-Alexandre; Earle, Kristen; Frivold, Collrane; Jarrahian, Courtney
- Relation
- Frontiers in Public Health Vol. 10, no. 809675
- Publisher Link
- http://dx.doi.org/10.3389/fpubh.2022.809675
- Publisher
- Frontiers Research Foundation
- Resource Type
- journal article
- Date
- 2022
- Description
- Measles and rubella microarray patches (MR-MAPs) are critical in achieving measles and rubella eradication, a goal highly unlikely to meet with current vaccines presentations. With low commercial incentive to MAP developers, limited and uncertain funding, the need for investment in a novel manufacturing facility, and remaining questions about the source of antigen, product demand, and regulatory pathway, MR-MAPs are unlikely to be prequalified by WHO and ready for use before 2033. This article describes the current progress of MR-MAPs, highlights challenges and opportunities pertinent to MR-MAPs manufacturing, regulatory approval, creating demand, and timelines to licensure. It also describes activities that are being undertaken by multiple partners to incentivise investment in and accelerate the development of MR-MAPs.
- Subject
- measles; vaccine; rubella; microarray patches; innovation; SDG 3; SDG 9; Sustainable Development Goals
- Identifier
- http://hdl.handle.net/1959.13/1483157
- Identifier
- uon:51082
- Identifier
- ISSN:2296-2565
- Rights
- © 2022 Hasso-Agopsowicz, Crowcroft, Biellik, Gregory, Menozzi-Arnaud, Amorij, Gilbert, Earle, Frivold, Jarrahian, Mvundura, Mistilis, Durrheim and Giersing. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY (https://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Language
- eng
- Full Text
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Goal 9: Industry, Innovation and Infrastructure
Goal 3: Good Health and Well-Being
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | ATTACHMENT02 | Publisher version (open access) | 695 KB | Adobe Acrobat PDF | View Details Download |